Whether (no pun intended) it’s climate change or other factors, it’s always difficult to discern when to prune your rose bushes and when to patiently wait. Ideally, you want to wait until any hints of freezing temperatures in your area are no longer a threat. Pruning wakes up your sleeping beauties and encourages them to get busy blooming. If this process begins and then a freeze stuns them, your rose bushes are at risk of dying or being exposed to other issues. Although, if you have an established rose bush, it will probably recover just fine, but for ones younger than a year or two in the ground, I would recommend holding off on pruning. Better safe than sorry! Personally, I find it always tempting on Spring-like days to get out there and clip away, but the lows at night, not to mention a last-minute snowfall, could seriously damper the fruits of my labor.
With all that said, when is it safe to prune? Some say wait till you see bud eyes swelling or little red leaves popping out.

Forsythia {photo credit: unknown}
Probably the most reliable indication of when to prune your roses, at least for gardening zones 6-7 such as mine in Pennsylvania and Maryland, is to wait on the forsythias to bloom. When you see those sprawling bushes bursting in glorious yellow, know that it’s time to pull out the pruners!
In the meantime, since you are probably like me anxious to assist your rose darlings before Spring officially begins, you can start clearing away debris and dead leaves that may have congregated in your garden beds. You can also sharpen your pruners and loppers in advance, and stock up on soil, pots, fertilizer, and other gardening supplies. I also call around to see who has the best deals on mulch.
Different regions prune in different calendar months. As for me and my garden, we’ll wait on the forsythia factor!
PRUNING BY REGION
Northeast / Mid-Atlantic: March or April (once)
Southeast: January & August (twice)
Southcentral / Lower Midwest: February & August (twice)
Midwest / Plains: March or April & August (twice)
Pacific Northwest: February or March (once)
Southwest / California: January or February & August (twice)